S-4 Andarine by Enhanced Athlete is an anabolic supplement that is intended for the gym shelves of those individuals who are bodybuilding enthusiasts.
S-4 (Andarine) or Acetamidoxolutamide, is a SARM (Selective Androgen Receptor Modulator). The term is quite intimidating for a newcomer but for old school and pro, the supplement is a term associated with lean muscle development and fat loss.
The following review will highlight the S-4 Andarine as a supplement, how it works, its safety borders and its effectiveness for our worthy customers who are taking up the endeavor of the bodybuilding field.
About the company
Enhanced Athlete is a supplement manufacturing company that owns its products on a research basis and works on non-profit grounds. The profits earned are circulated again in further research and study for bringing forth-superior quality products and maintenance of quality.
The company proudly claims that their products are
- Researched based and proven for their efficacy
- Meet the safety margins for the consumers with no side effects
- Come at a cost that surpasses the competency level by any other brand in the market
The company does not indulge in diet trends or workout routines; rather their point of focus is solely on creating and designing of supplements via quality research work.
About the product
Primarily, let us clear the expression of the product. S-4 Andarine is one of the potent forms, belonging to SARM category of supplements.
SARM stands for ‘selective androgen receptor modulator’, which is a class of therapeutic agents with anabolic properties with reduced potency as androgens. This trait keeps the specific compound at an edge over other anabolic compounds in the following ways
- androgen-receptor specificity
- tissue selectivity (only skeletal muscles are targeted)
- the lack of steroid-related side effects as acne, liver damage, breast tissue development, and shrinking of the testicle in males, and deepening of the voice, a growth of hair on the face, stomach, upper back, and abnormal menstrual cycles in females
Selective androgen receptor modulators have the ability to differentiate and then function accordingly, between anabolic and androgenic activities and that is the reason behind its utilization in various medical therapeutic procedures as muscle-wasting diseases, osteoporosis, cancer, and hypogonadism, since the 1940s.
The term SARM has been controversial since its arrival on the medical field. The reason behind this argument lies with the steroidal form. However, in the early 1990s, researchers came up with the non-steroidal version of SARM that was protein based. This characteristic attributed to the effectiveness of SARM in targeting the cellular DNA that resulted in muscle build up by promoting the growth of muscles and reduced bone wastage, at the same time of losing fat.
“Unlike testosterone cypionate, SARMS are more than 200 times more powerful in muscle stimulation and 80 times more selective for muscle”
Since then, the non-steroidal variety of SARM has been the choice of supplement for bodybuilding, power lifting and a whole host of other sports. SARM has been put on trial for their safety margin and no harm is suggested yet, thus making them the future of anabolic therapy in many fields.
When compared with testosterone therapy, SARM agents do not result in side effects usually associated with the former, being an upgraded version of anabolic steroids. SARM link to the same receptors as testosterone or other steroids but being protein in nature, they are specific to the skeletal muscle receptors only and thus do not bring about the side effects. The overall outcome is skeletal muscle mass and physical endurance is enhanced.
SARM is also believed to result in
- dose-dependent improvements in bone mineral density
- motorized strength
- decrease body fat
- increase lean body mass
Mechanism of action of S-4 Andarine
Andarine S-4 was originally created for the therapeutic treatment of osteoporosis, muscle wasting, and benign prostate hypertrophy. It is sold backed by research studies as a chemical that is widely prevalent among athletes to gain lean muscle mass without the side effects of anabolic steroids. It is also utilized as part of steroid stacks to improve a cycle without side effects. Andarine works by attaching itself to androgen receptors with observed anabolic activity. The uses of S-4 Andarine can be categorized as medical and athletic.
- restoration of muscle mass
- increased bone density
- effective fat losing outcomes in a shorter duration of time and with fewer side effects than anabolic steroids
- builds lean muscle mass with increased strength and endurance
- does not create water weight
- does not dry out joints
- increases bone density
- can be used in between steroid cycles to maintain the muscle mass
- can be used on its own or by stacking with other compounds to multiply the outcome. Stacking can be done for fat cutting, endurance gains or as anabolic steroid stack.
Benefits of S-4 Andarine by Enhanced Athlete
The benefits of S-4 Andarine by Enhanced Athlete will be discussed with SARM in the background
- increased lean muscle mass
- muscle loss prevention during the cutting phase
- does not affect bone density
- enhanced physical strength and endurance
- helps in speedy recovery
- avoidance of joint stress
- can be used by women too
Some other organ related benefits are
- non-toxic to liver
- no risk of prostate hypertrophy
- does not hamper the hypothalamic-pituitary-gonadal axis
- shares similar effects as testosterone without side effects
- no conversion into dihydrotestosterone or estrogen
- stimulates fat loss
- no post cycle therapy is required
- a decreased time interval between different cycles
Side effects of S-4 Andarine
A responsible and conscientious use of S-4 Andarine will not lead to any side effects that would cause discontinuation of use. However, our eyes have androgen receptors and Andarine affinity for androgen receptors causes it to accumulate over the site. This poses a problem of adjusting to darkness from a well-lit area or the development of a yellow tint to eyes. The side effect is temporary and goes away within few days to a week time on discontinuation. Nevertheless, if it becomes too much to cope, the dose can always be adjusted.
Dosage schedule of S-4 Andarine
The half-life (time taken by the body to get it out of the system) of Andarine is 4-6 hours, therefore a divided dose is a better option. A total of 50-75 mg per day can be taken, starting from 25mg and then increasing gradually until the maximum dose is achieved or any eye symptoms develop. The dose should be adjusted according to individual requirements and threshold level.
Legal status of S-4 Andarine and other SARM compounds
SARM is included in the prohibited items list of the World Anti Doping Agency since 2008 due to their misuse by the athletes to increase their athletic performance. With the advent of the non-steroidal variety of SARM in 1998, many therapeutic agents have been subjected to clinical trials and studies but their status as clinically prescribed drugs for human consumption has not been awarded yet.
SARM is not classified as legal ingredients in dietary supplements either.
“As an example, in 2014, the U.S. Food and Drug Administration (FDA) issued a warning letter to a dietary supplement company as one of their products contained an unapproved SARM ingredient, Ostarine. According to the letter, a dietary supplement cannot include a substance that is being investigated as a new drug candidate; in this case, Ostarine”
Regardless of all these facts, SARM as S-4 Andarine could be the next whim in medical as well as athletic fields owing to their established role in combating conditions like muscular dystrophy, bone degeneration, inhibition of cancer cells replication. They have a role to play in regulation of libido and their unique ability of tissue selectivity makes them a superior therapeutic choice. Regarding its safety and efficacy, following should be enough a verdict for individual use
“In the Oxford Journal of Gerontology Series A: Biological Sciences and Medical Sciences, the popular nonsteroidal SARM LGD 4033 (Ligandrol) has been recently studied for its effectiveness and safety in healthy young men. Results were favorable indicated by hormone and lipid levels returning to normal without the use of a post cycle therapy. No dangers were detected throughout the study. Although there was noticeable suppression in testosterone and HDL cholesterol, it was not significant enough to cause adverse reactions. Because LGD 4033 is considered one of the strongest and most potent nonsteroidal SARMs available, it is not likely that less potent SARMs will produce any harmful effects (Bhasin, 2010)”.
The conclusion on S-4 Andarine is; get it from a well-reputed source as the product is available via online retailers, some of which may be a simple rip off, therefore paying a little extra would save you on your well-being and health security.